Skip to main content R&D Project Manager View details＋
Responsibilities
- This role combines core CGT clinical project management and clinical research monitoring responsibilities and independently coordinates end-to-end trial delivery to support compliant, efficient and timely execution.
- Project management: lead CGT clinical trial planning and delivery from initiation and protocol implementation through schedules, resources, budgets, quality and risk; coordinate sponsors, clinical sites, ethics committees and regulators; report progress, risks and corrective actions in accordance with GCP, company SOPs and the protocol.
- Clinical monitoring: independently manage site selection, initiation, enrolment, follow-up and close-out; perform site initiation, routine monitoring and close-out visits; verify data authenticity, completeness and accuracy; protect participant rights; identify issues and track corrective actions to closure; support ethics submissions, filings, audits and inspections.
- Draft, review and archive project plans, monitoring reports, close-out documents and submission materials; coordinate with medical, regulatory, data and quality teams and improve delivery processes.
Requirements
- Bachelor's degree or above in clinical medicine, pharmacy, bioengineering, biotechnology or a related biomedical discipline.
- Complete CRA experience and familiarity with the full clinical monitoring lifecycle, plus CGT clinical project management experience and the ability to independently cover both PM and CRA responsibilities. Experience in cell therapy, gene therapy, stem cells or oncolytic viruses is preferred.
- Strong planning, communication, coordination, problem-solving and resilience; careful, responsible and collaborative.
Cell Therapy Manufacturing Engineer View details＋
Responsibilities
- Prepare and passage cells.
- Conduct experiments using cell biology techniques and record data.
- Apply cell biology and molecular biology laboratory techniques.
- Follow standard operating procedures and laboratory safety requirements.
Requirements
- Bachelor's degree or above in biomedicine or a related field.
- Two or more years of relevant laboratory experience is preferred.
- Familiarity with murine DC preparation.
- Good communication and teamwork skills.
Bioinformatics Engineer View details＋
Responsibilities
- Lead WES, transcriptomic and immune-microenvironment multi-omics analyses for solid-tumor and peripheral-blood samples and build tumor genomic libraries.
- Detect and annotate somatic variants, homologous recombination deficiency and somatic/germline variants in DNA damage response pathways.
- Develop immunotherapy suitability assessments integrating TMB, MSI, HLA-I typing, intratumor heterogeneity and neoantigen prediction.
- Model associations between chemotherapy-sensitivity SNPs and TCR repertoire diversity and produce clinical-grade personalized reports with medical interpretation.
- Design and optimize neoantigen prediction algorithms, particularly HLA-peptide binding affinity and immunogenicity models; integrate genomic variants, transcript abundance and mass-spectrometry validation.
- Build a structured tumor neoantigen knowledge database for HLA typing, TCR sequences and epitopes, and work with laboratory teams to validate predictions against in-vitro immune activation.
Requirements
- Master's degree or above in bioinformatics, computational biology, genomics or a related field.
- Hands-on experience with tumor multi-omics workflows including WES/WGS, RNA-seq and immunohistochemistry data.
- Proficiency in Python/R and familiarity with GATK, STAR, ANNOVAR and public databases such as TCGA/ICGC.
- Knowledge of core immunotherapy indicators and neoantigen prediction tools such as NetMHCpan and MHCflurry.
- Experience with neoantigen algorithms and TensorFlow/PyTorch, DDR/HRD or TCR repertoire analysis, relevant publications or patents, or clinical report/IVD/LDT development is preferred.
Clinical Research Associate (CRA) View details＋
Responsibilities
- Monitor clinical trials, including ethics submissions, site initiation, investigational product management, monitoring, data cleaning and site close-out.
- Manage CROs and other vendors and coordinate company resources to execute studies according to the protocol and implementation plan.
- Control critical site milestones and support trial quality and timelines.
- Help prepare study documentation, investigational products and materials.
- Maintain effective relationships with investigators, institutions, ethics committees and other partners.
Requirements
- Bachelor's degree or above in clinical medicine, pharmacy or a related discipline.
- At least two years of CRA experience; innovative-drug project experience is preferred.
- GCP certification.
- Strong interpersonal, communication and verbal skills.
